This ap­pli­ca­ti­on brief high­lights the use of a Plas­mi­on SICRIT® cold plas­ma io­niza­ti­on source cou­pled to a Wa­ters ACQUITY QDa De­tec­tor to di­rect­ly as­sess the vo­la­ti­le or­ga­nic pro­files in real-time of bio­ba­sed pla­s­tic bags.